Pd-Ni/SiNWs electrode for nonenzymatic glucose detection
-
摘要: 在镍修饰的硅纳米线阵列电极上电沉积金属钯微粒,用于葡萄糖的非酶检测;并通过电子扫描显微镜(SEM)和X射线能谱分析(EDS)对电极表面的形貌进行了表征,采用循环伏安法和恒电位计时电流法测试传感器的性能参数.在0.1 M的KOH碱性介质中,恒定电势+0.19 V,钯-镍修饰的硅纳米线阵列电极对葡萄糖的电化学氧化的灵敏度为302.2 AmM-1cm-2,检测极限(S/N=3)达到4.9 M,而且对抗坏血酸(AA)、尿酸(UA)等干扰物质具有良好的抗干扰能力.实验表明,这种新型电极很有潜力用于葡萄糖的非酶检测.
-
关键词:
- 葡萄糖非酶检测 /
- 电沉积 /
- 钯镍修饰硅纳米线阵列 /
- 循环伏安 /
- 恒电位计时电流
Abstract: A nonenzymatic glucose sensor was fabricated by electroplating palladium particles on a nickel modified silicon nanowires(Ni/SiNWs) array electrode. The morphology of the Pd-Ni/SiNWs electrode was characterized by scanning electron microscope (SEM) and energy-dispersive X-ray spectroscopy (EDS) analysis. The performance of this sensor was characterized by cyclic voltammetry (CV) and fixed potential amperometry techniques. Under the fixed potential of +0.19 V, the sensitivity of the electrochemical oxidation for glucose is 302.2 AmM-1cm-2 and the detection limit (S/N ratio=3) is 4.9 M in the 0.1 M KOH alkaline electrolyte. Furthermore, the electrode shows good resistance for the interfering species such as the ascorbic acid (AA) and uric acid (UA). This novel sensor has great potential for the determination of glucose. -
[1] [1] SU S, HE Y, SONG S P, et al. A silicon nanowire-based electrochemical glucose biosensor with high electrocatalytic activity and sensitivity [J]. Nanoscale, 2010(2): 1704-1707.[2] QIU C C, WANG X, LIU X Y, et al. Direct electrochemistry of glucose oxidase immobilized on nanostructured gold thin films and its application to bioelectrochemical glucose sensor [J]. Electrochimica Acta, 2012, 67: 140-146. [3] YANG M, YANG Y, LIU Y, et al. Platinum nanoparticles-doped sol-gel/carbon nanotubes composite electrochemical sensors and biosensors [J]. Biosens Bioelectron, 2006, 21: 1125-1131.[4] ABDOLLAH S, ENSIYEH S, ABDOLLAH N, et al. Immobilization of glucose oxidase on electrodeposited nickel oxide nanoparticles: Direct electron transfer and electrocatalytic activity [J]. Biosensors and Bioelectronics, 2007, 22: 3146-3153.[5] CHEN X M, LIN Z J, CHEN D J, et al. Nonenzymatic amperometric sensing of glucose by using palladium nanoparticles supported on functional carbon nanotubes [J]. Biosens Bioelectron, 2010, 25: 1803-1808.[6] HINDLE P H, NIGRO S, ASMUSSEN M, et al. Amperometric glucose sensor based on platinum-iridium nanomaterials [J]. Electrochemistry Communications, 2008, 10: 1438-1441.[7] CHEN L Y, LANG X Y, FUJITA T, et al. Nanoporous gold for enzyme-free electrochemical glucose sensors [J]. Scripta Materialia, 2011, 65: 17-20.[8] CUI H F, YE J S, ZHANG W D, et al. Selective and sensitive electrochemical detection of glucose in neutral solution using platinum-lead alloy nanoparticle/carbon nanotube nanocomposites [J]. Anal Chim Acta, 2007, 594: 175-183.[9] SHI J, CI P L, WANG F, et al. Nonenzymatic glucose sensor based on over-oxidized polypyrrole modified Pd/Si microchannel plate electrode [J]. Biosensors and Bioelectronics, 2011, 26: 2579-2584.[10] MIAO F J, TAO B R, SUN L, et al. Amperometric glucose sensor based on 3D ordered nickel-palladium nanomaterial supported by silicon MCP array [J]. Sens Actuators B, 2009, 141: 338-342.[11] LU L M, ZHANG L, QU F L, et al. A nano-Ni based ultrasensitive nonenzymatic electrochemical sensor for glucose: enhancing sensitivity through a nanowire array strategy [J]. Biosens Bioelectron, 2009, 25: 218-223.[12] ZHANG Y C, SU L, MANUZZI D, et al. Ultrasensitive and selective non-enzymatic glucose detection using copper nanowires [J]. Biosensors and Bioelectronics, 2012,31: 426-432.[13] WAN L J, GONG W L, JIANG K W, et al. Preparation and surface modification of silicon nanowires under normal conditions [J]. Appl Surf Sci, 2008, 254: 4899-4907.[14] TAO B R, ZHANG J, HUI S C, et al. An amperometric ethanol sensor based on a Pd-Ni/SiNWs electrode [J]. Sens Actuators B, 2009, 142: 298-303.[15] HUI S C, ZHANG J, CHEN X J, et al. Study of an amperometric glucose sensor based on Pd-Ni/SiNW electrode [J]. Sensors and Actuators B, 2011, 155: 592-597.[16] LIANG Z X, ZHAO T S, XU J B, et al. Mechanism study of the ethanol oxidation reaction on palladium [J]. Electrochimica Acta, 2009, 54: 2203-2208.[17] MENG L, JIN J, YANG G X, et al. Nonenzymatic electrochemical detection of glucose based on palladium-single-walled carbon nanotube hybrid nanostructures [J]. Anal Chem, 2009, 81: 7271-7280.[18] SATHEESH BABU T G, RAMACHANDRAN T. Development of highly sensitive non-enzymatic sensor for the selective determination of glucose and fabrication of a working model [J]. Electrochim Acta, 2010, 55: 1612-1618.[19] PARK S, CHUNG T D, KIM H C. Nonenzymatic glucose detection using mesoporous platinum [J]. Anal Chem, 2003, 75: 3046-3049.
点击查看大图
计量
- 文章访问数: 2373
- HTML全文浏览量: 63
- PDF下载量: 2292
- 被引次数: 0