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Issue 6
Nov.  2011
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WANG Qing, YUAN Ping, MAO Ren-gang, WANG Ju-yong, ZHENG Zhan. Isolation and identification of the fungi which can convert Panax Notoginseng extract into ginsenoside Rg3[J]. Journal of East China Normal University (Natural Sciences), 2011, (6): 115-121,151.
Citation: WANG Qing, YUAN Ping, MAO Ren-gang, WANG Ju-yong, ZHENG Zhan. Isolation and identification of the fungi which can convert Panax Notoginseng extract into ginsenoside Rg3[J]. Journal of East China Normal University (Natural Sciences), 2011, (6): 115-121,151.

Isolation and identification of the fungi which can convert Panax Notoginseng extract into ginsenoside Rg3

  • Received Date: 2010-11-01
  • Rev Recd Date: 2011-02-01
  • Publish Date: 2011-11-25
  • Twenty-three strains were isolated from soil where ginseng grew. The Panax Notoginseng extract were analyzed by TLC and HPLC. There were nine strains which can converte Panax Notoginseng extract into highly active ginsenoside, among which the TR-20 was the best one. Moreover, the TR-20 can convert Panax Notoginseng extract into ginsenoside Rg3(190.2 mg/L). The TR-20 was Aspergillus (Aspergillus sp.) with observation of morphology and cultural characteristics.
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  • [1]
    [1] FENG Y L. Panax saponin and tumor [J]. Foreign Med Sci Oncol, 2005, 32(9): 665-667.

    [2] LEE J Y, SHIN J W, CHUN K S. Antitumor promotional elfects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol-type ginsenosides in mouse skin [J]. Carcinogenesis, 2005, 26(2): 359-367.

    [3] 赵文杰,陈迪,倪劲松,等. 20(S)-人参皂苷Rg3对前列腺癌PC-3M细胞的诱导凋亡作用[J].中国药理学通报,2009,25(2):235-238.

     ZHAO W J, CHEN D, NI J S, et al. Study on PC-3M cell apoptosis induced by 20(s)-ginsendoside Rg3 in prostate carcinoma[J]. Chinese Pharmacological Bulletin, 2009,25(2):235-238.

    [4] 〖JP2〗韩颖,姜彬慧,胡筱敏,等. Fusarium sacchari转化三七茎叶皂苷的稀有抗肿瘤成分[J].中草药,2007,38(6):830-832.〖JP〗

     HAN Y, JIANG B H, HU X M, et al. Fusarium sacchari transform rare anti-tumor composition in Panax Notoginseng stem and leaf saponin[J]. Chinese herbal medicine, 2007, 38(6): 830-832.

    [5] RUAN C C, ZHANG H, ZHANG L X. Biotransformation of ginsenoside Rf to Rh1 by recombinant β-glucosidase[J]. Molecules, 2009, 14: 2043-2048.

    [6] CHENG L Q, NA L R, BANG M H, et al. Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514[J]. Phytochemistry, 2008, 69: 218-224.

    [7] 白龙律,臧蕴霞,尹成日.微生物转化人参皂苷Rb1为Rg3的研究[J].延边大学学报:自然科学版,2009,35(2):141-144.

     BAI L L, ZANG Y X, YIN C R. Microbiological transform ginsenoside Rb1 into Rg3[J]. Journal of Yanbian University: Natural Science Edition, 2009, 35(2): 141-144.

    [8] DONG A L, CUI Y J, GUO H Z. Microbiological transformation of ginsenoside Rg1[J] . Journal of Chinese Pharmaceutical Sciences, 2001, 10(3): 115-118.

    [9] 付建国.人参皂苷微生物转化的研究[D].长春:吉林农业大学,2004.

     FU J G. The study of microbial transformation of ginsenoside[D]. Changchun: Jilin Agricultural University, 2004.                                                                      [10] 宛晓春,汤坚,丁霄霖.β-葡萄糖苷酶产酶菌种的选育[J].安徽农业大学学报,1997,24(1): 77-80.

     WAN X C, TANG J, DING X L. Selection of an Aspergillus niger strain producing β-glucosidase[J]. Journal of Anhui Agricultural University, 1997, 24(1): 77-80.

    [11] 杨胜远,刘玉燕,梁志群.β-葡萄糖苷酶产生菌的分离筛选[J].工业微生物,2002,32(4),36-38.

     YANG Y S, LIU Y Y, LIANG Z Q. Isolation and screening of β-glucosidase producing strain[J]. Industrial Microbiology, 2002, 32(4): 36-38.

    [12] 廖美德,许耀才,陈华癸.棒曲霉H-211的形态特征的研究[J].湖北农学院学报,1995,15(2):102-104.

     LIAO M D, XU Y C, CHEN H K. The morphological character of Aspergillus clavatus strain H-211[J]. Journal of Hubei Agricultural College, 1995, 15(2): 102-104.

    [13] 廖美德.棒曲霉H-211生理特性的研究[J].湖北农学院学报,1997,17(4):279-282.

     LIAO M D. Studies on the physiological properties of Aspergillus clavatus strain H-211[J]. Journal of Hubei Agricultural College, 1997, 17(4): 279-282.
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