Along the Min River, there are more than five areas with relatively large area and well habitant and breeding for birds.Human-induced land use and land cover changes in wetland areas,such as urban construction and flood-proof and transportation projects conversing wetlands into non-wetlands, has significant impacts on landscape pattern of wetlands.This paper applied multiple spatial data and information from remote sensing and maps, as well as geographic information system modeling and landscape ecological approaches to reveal the changes of landscape of wetland in the study area from 1986 to 2003.The results showed: (1) The regional wetland landscape types were characterized into 12 types，including natural wetland, man-made wetland and non-wetland.The landscape diversity index and Shannon’s Evenness index increased in the past 17 years, while the numbers of patches increased, the areas of the nature wetland decreased and that of man-made wetland and non-wetland increased.The fragmentation of landscape of wetland in the study area enhanced steadily due to increasing mankind activities.(2) On respect of individual patches index, wetlands’ patches mean area declined 28.99 percents from 1986 to 2003 and density of patches increased 40.87 percents on the same period, and fractal dimension and shape index which reflected the shape of patches had increased in temporal scales, for the shape of patches more complex under the mankind disturbance.(3) The spatial variation of wetland landscape along the river was affected by a suite of natural and anthropogenic factors, such as hydrological and climate factors and various human activities.Urban construction and flood-proof projects were key factors to natural wetland conversation to non-wetland.Rapid population growth and economic development have significantly impact the spatial pattern of the landscape of study areas.