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CHEN Zi-zhan, GUAN Xi-xia, ZHENG Zu-biao, ZOU Xin-zhuo. α-Halogenation of carbonyl compounds with 1,3-dihalo-5,5-dimethylhydantoin[J]. Journal of East China Normal University (Natural Sciences), 2010, (4): 125-130.
Citation:
CHEN Zi-zhan, GUAN Xi-xia, ZHENG Zu-biao, ZOU Xin-zhuo. α-Halogenation of carbonyl compounds with 1,3-dihalo-5,5-dimethylhydantoin[J]. Journal of East China Normal University (Natural Sciences), 2010, (4): 125-130.
CHEN Zi-zhan, GUAN Xi-xia, ZHENG Zu-biao, ZOU Xin-zhuo. α-Halogenation of carbonyl compounds with 1,3-dihalo-5,5-dimethylhydantoin[J]. Journal of East China Normal University (Natural Sciences), 2010, (4): 125-130.
Citation:
CHEN Zi-zhan, GUAN Xi-xia, ZHENG Zu-biao, ZOU Xin-zhuo. α-Halogenation of carbonyl compounds with 1,3-dihalo-5,5-dimethylhydantoin[J]. Journal of East China Normal University (Natural Sciences), 2010, (4): 125-130.
α-Bromination of aliphatic ketones using 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) in methanol at room temperature was described. α-Chlorination of aliphatic ketones, β-keto-esters and malonic ester using 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) and p-toluenesulfonic acid in acetonitrile at 25 ℃ was also reported. β-Keto-esters and dimethyl malonate give α-monochloroproducts in high yields (87%~96%).