［1］ VINEIS P, HUSGAFVEL-PURSIAINEN K. Air pollution and cancer: biomarker studies in human populations［J］. Carcinogenesis, 2005, 26: 1846-1855.

［2］ MATHIJSSEN R H, VAN SCHAIK R H. Genotyping and phenotyping cytochrome P450: perspectives for cancer treatment［J］. Eur J Cancer, 2006, 42: 141-148.

［3］ NAKACHI K, IMAI K, HAYASHI S, et al. Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population［J］. Cancer Res, 1993, 53(13): 2994-2999.

［4］ ISHIBE N, WIENCKE J K, ZUO Z F, et al. Susceptibility to lung cancer in light smokers associated with CYP1A1 polymorphisms in Mexican- and African-Americans［J］. Cancer Epidemiol Biomarkers Prev, 1997, 6(12): 1075-1080.

［5］ TAIOLI E, FORD J, TRACHMAN J, et al. Lung cancer risk and CYP1A1 genotype in African Americans［J］.Carcinogenesis, 1998, 19(5): 813-817.

［6］ GSUR A, HAIDINGER G, HOLLAUS P, et al. Genetic polymorphisms of CYP1A1 and GSTM1 and lung cancer risk［J］.Anticancer Res, 2001, 21(3C): 2237-2242.

［7］ ALEXANDRIE A K, NYBERG F, WARHOLM M, et al. Influence of CYP1A1, GSTM1, GSTT1, and NQO1 genotypes and cumulative smoking dose on lung cancer risk in a Swedish population ［J］.Cancer Epidemiol Biomarkers Prev, 2004, 13(6): 908-914.

［8］ 宋南，谭文，唐槐静，等.中国人细胞色素P4501A1基因变异与吸烟相关性肺癌的风险［J］.癌症, 1999, 18(5): 495-498.

SONG N , TAN W , TANG H J, et al. Impact of cytochrome P450A1 gene mutations on the risk of development of lung cancer in a Chinese population［J］. Chinese Journal of Cancer, 1999, 18(5): 495-498.

［9］ SONG N, TAN W, XING D, et al. CYP 1A1 polymorphism and risk of lung cancer in relation to tobacco smoking: a case-control study in China［J］. Carcinogenesis, 2001, 22(1): 11-16.

［10］ QUIONES L, LUCAS D, GODOY J, et al. CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people［J］. Cancer Lett, 2001, 174(1): 35-44.

［11］ WRENSCH M R, MIIKE R, SISON J D, et al. CYP1A1 variants and smoking-related lung cancer in San Francisco Bay area Latinos and African Americans［J］. Int J Cancer, 2005, 113(1): 141-147.

［12］ SHAH P P, SINGH A P, SINGH M, et al. Interaction of cytochrome P4501A1 genotypes with other risk factors and susceptibility to lung cancer ［J］.Mutat Res, 2008, 639(2008): 1-10.

［13］ KIHARA M, KIHARA M, NODA K. Risk of smoking for squamous and small cell carcinomas of the lung modulated by combinations of CYP1A1 and GSTM1 gene polymorphisms in a Japanese population ［J］. Carcinogenesis, 1995, 16(10): 2331-2336.

［14］ CANTLAY A M, LAMB D, GILLOOLY M, et al. Association between the CYP1A1 gene polymorphism and susceptibility to emphysema and lung cancer ［J］. Clin Mol Pathol, 1995, 48(4): M210-M214.

［15］ SUGIMURA H, WAKAI K, GENKA K, et al. Association of Ile462Val (Exon 7) polymorphism of cytochrome P450 IA1 with lung cancer in the Asian population: further evidence from a case-control study in Okinawa［J］. Cancer Epidemiol Biomarkers Prev, 1998, 7(5): 413-417.

［16］ LONDON S J, YUAN J M, COETZEE G A, et al. CYP1A1 I462V genetic polymorphism and lung cancer risk in a cohort of men in Shanghai［J］.Cancer Epidemiol Biomarkers Prev, 2000, 9(9): 987-991.

［17］ CHEN S, XUE K, XU L,et al. Polymorphisms of the CYP1A1 and GSTM1 genes in relation to individual susceptibility to lung carcinoma in Chinese population ［J］. Mutat Res, 2001, 458(2001): 41-47.

［18］ SUNAGA N, KOHNO T, YANAGITANI N, et al. Contribution of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility［J］. Cancer Epidemiol Biomarkers Prev, 2002, 11(8): 730-738.

［19］ LARSEN J E, COLOSIMO M L, YANG I A, et al. Risk of non-small cell lung cancer and the cytochrome P4501A1 Ile462Val polymorphism ［J］. Cancer Causes Control, 2005, 16(5): 579-585.

［20］ KUMAR M, AGARWAL S K, GOEL S K. Lung cancer risk in north Indian population: role of genetic polymorphisms and smoking ［J］. Mol Cell Biochem, 2009, 322(2009): 73-79.

［21］ TIMOFEEVA M N, KROPP S, SAUTER W, et al.CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences［J］. Carcinogenesis., 2009, 30(7): 1161-1169.

［22］ SHIELDS P G, CAPORASO N E, FALK R T, et al. Lung cancer, race, and a CYP1A1 genetic polymorphism［J］.Cancer Epidemiol Biomarkers Prev,1993, 2(3): 481-485.

［23］ GARCIA-CLOSAS M, KELSEY K T, WIENCKE J K, et al. A case-control study of cytochrome P450 1A1, glutathione S-transferase M1, cigarette smoking and lung cancer susceptibility ［J］.Cancer Causes Control,1997, 8(4): 544-553.

［24］ YIN L, PU Y, LIU T Y, et al. Genetic polymorphisms of NAD(P)H quinone oxidoreductase, CYP1A1 and microsomal epoxide hydrolase and lung cancer risk in Nanjing, China［J］.Lung Cancer, 2001, 33(2003): 133-141.

［25］ WANG J, DENG Y, LI L, et al. Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: a case-control study in Chinese population ［J］.Cancer Sci, 2003, 94(5): 448-452.

［26］ 汪保国,陈思东,周卫平,等.细胞色素P4501A1和谷胱苷肽硫转移酶基因多态性与肺癌关系的病例对照研究［J］.中华肿瘤杂志,2004, 26(2): 93-97.

WANG B G,CHEN S D, ZHOU W P, et al. A case control study on the impact of CYP450 MSPI and GST-M1 polymorphisms on the risk of lung cancer［J］. Chinese Journal of Oncology, 2004, 26(2): 93-97.

［27］ SREEJA L, SYAMALA V, HARIHARAN S, et al. Possible risk modification by CYP1A1, GSTM1 and GSTT1 gene polymorphisms in lung cancer susceptibility in a South Indian population［J］.J Hum Genet,2005, 50(12): 618-627.

［28］ 顾艳斐，张宗德，张树才，等.细胞色素P450基因多态性与肺癌易感性的相关性分析［J］.中华医学杂志, 2007, 87(43): 3064-3068.

GU Y F, ZHANG Z D, ZHANG S C, et al. Combined effects of genetic polymorphisms in cytochrome P450s and GSTM1 on lung cancer susceptibility［J］.National Medical Journal of China, 2007, 87(43): 3064-3068.

［29］ HONMA H N, DE CAPITANI E M, BARBEIRO ADE S, et al. Polymorphism of the CYP1A1*2A gene and susceptibility to lung cancer in a Brazilian population ［J］. J Bras Pneumol,2009, 35(8): 767-772.

［30］ KIYOHARA C, WAKAI K, MIKAMI H, et al. Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of environmental tobacco smoke and lung cancer: a case-control study in Japanese nonsmoking women［J］. Int J Cancer,2003, 107(1): 139-144.

［31］ SUGIMURA H, SUZUKI I, HAMADA G S, et al. Cytochrome P-450 IA1 genotype in lung cancer patients and controls in Rio de Janeiro, Brazil［J］. Cancer Epidemiol Biomarkers Prev, 1994, 3(2): 145-148.

［32］ KAWAJIRI K, NAKACHI K, IMAI K, et al. Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P450IA1 gene［J］. FEBS Lett, 1990, 263(1): 131-133.

［33］ HUNG R J, BOFFETTA P, BROCKM L J, et al.CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis［J］.Carcinogenesis. 2003, 24(5): 875-882.

［34］ HUNG R J, MCKAY J D, GABORIEAU V, et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25［J］.Nature, 2008, 452(7187): 633-637.

［35］ THORGEIRSSON T E, GELLER F, SULEM P, et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease［J］.Nature, 2008, 452(7187): 638-642.

［36］ AMOS C I, WU X, BRODERICK P, et al. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1［J］. Nat Genet, 2008, 40(5): 616-622. 

［37］ SHI X, ZHOU S, WANG Z, et al. CYP1A1 and GSTM1 polymorphisms and lung cancer risk in Chinese populations: a meta-analysis［J］.Lung Cancer, 2008, 59(2): 155-163.

［38］ CROFTS F, TAIOLI E, TRACHMAN J, et al. (1994) Functional significance of different human CYP1A1 genotypes［J］. Carcinogenesis, 1994, 15(12): 2961-2963.

［39］ MOONEY L A, BELL D A, SANTELLA R M, et al. Contribution of genetic and nutritional factors to DNA damage in heavy smokers［J］.Carcinogenesis 18(3): 503-509.

［40］ NERURKAR P V, OKINAKA L, AOKI C, et al. CYP1A1,GSTM1,and GSTP1 genetic polymorphisms and urinary 1-hydroxypyrene excretion in non-occupationally exposed individuals［J］. Cancer Epidemiol Biomarkers Prev .2000, 9(10): 1119-1122.

［41］ ALEXANDROV K, CASCORBI I, ROJAS M, et al. CYP1A1 and GSTM1 genotypes affect benzo［a］pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation［J］. Carcinogenesis, 2002, 23(12): 1969-1977.