Research on separation method of highly polar compound DMC and impurities in it by HILIC

HAN Bing-bing; WANG Cui-cui; LI Xin-jun; ZOU Xin-zhuo

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Nov. 2011

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HAN Bing-bing, WANG Cui-cui, LI Xin-jun, ZOU Xin-zhuo. Research on separation method of highly polar compound DMC and impurities in it by HILIC[J]. Journal of East China Normal University (Natural Sciences), 2011, (6): 132-138.

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HAN Bing-bing, WANG Cui-cui, LI Xin-jun, ZOU Xin-zhuo. Research on separation method of highly polar compound DMC and impurities in it by HILIC[J]. Journal of East China Normal University (Natural Sciences), 2011, (6): 132-138.

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Research on separation method of highly polar compound DMC and impurities in it by HILIC

1.
Department of Chemistry, East China Normal University, Shanghai 200062, China

Received Date: 2010-12-01
Rev Recd Date: 2011-03-01
Publish Date: 2011-11-25

Abstract

Abstract

HILIC method was established to separate and analyze highly polar compound methacryloyloxyethyl trimethyl ammonium chloride (DMC) and its impurities. Using two different chromatographic columns：HP-Cyano column and X-Bridge HILIC column，highly polar compound DMC and its impurities were all well separated by gradient elution using acetonitrile and water as mobile phase. With the two different chromatographic columns, four impurities in DMC were separated, such as dimethylaminoethyl methacrylate (DM),methacrylic acid (MAA), choline chloride (CC) and Hydroquinone monomethyl ether (MQ). This method has higher practical value, which can be used effectively in separated highly polar compounds.

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References(1)

References

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